Prof. Hiroyuki NojiATP synthase, the major supplier of ATP in a cell, shows remarkable function and elegant structure. One feature of ATP synthase that discriminates it from other molecular machines is that this enzyme is able to interconvert two totally different forms of potential energy; the proton-motive force and the phosphate-transfer potential of ATP. A key mechanism for this unique capability is the rotation of ATP synthase inner subunit complex. This feature has been the primary topic of interest for many researchers not only of the biological disciplines, but also of theoretical chemistry, non-equilibrium physics and even nanotechnology. The regulatory mechanisms of ATP synthase and other related enzymes are also the focus of interest of this field.

In 2014, we held the 1st Tokyo ATPase Workshop for two days, June 2-3, with the aim to stimulate the discussion on the molecular mechanism of ATP synthase and other related enzymes. Many excellent talks including two keynote lectures by Nobel Prize laureates; Prof. John Walker (Chemistry, 1997) and Prof. Arieh Warshel (Chemistry, 2013) contributed to the great success of the 1st Tokyo ATPase Workshop.

Since the 1st Tokyo ATPase Workshop, this field has seen a rapid and dramatic growth for past 5 years, that includes the structural analysis of the whole complexes of ATP synthase and V-type ATPase at atomic resolution and the findings on variations in ATPase reaction mechanism. Thus, it would be very timely to hold the 2nd Tokyo ATPase Workshop. We invite many eminent scientists from various fields; biochemistry, structural biology, single-molecule biophysics, and theoretical biology. We also provide the opportunities for young researchers to display their posters.

The highlight of The 2nd Tokyo ATPase Workshop is the special joint program in collaboration with Tokyo College (, a new institute of the University of Tokyo that was established based on the initiative of President of The University of Tokyo, Prof. Makoto Gonokami. Prof. Sir John Walker will deliver the public lecture of Tokyo College that will be open not only to researchers, but also to undergraduate students and general public. Prof. Masasuke Yoshida will contribute to this program as a moderator.

A banquet is scheduled after the public lecture of Tokyo College. This would be the best opportunity for attendees to speak to the invited lecturers as well as other participants.

This workshop on ATPase is designed to offer a rare environment that brings together researchers of all levels to advance the field. I look forward to your participation.

With best regards,

Hiroyuki Noji

Chair of the Organizing Committee, the 2nd Tokyo ATPase Workshop
Professor at Department of Applied Chemistry
The University of Tokyo




Sanjo Conference Hall
The University of Tokyo

7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan


Secretariat for Tokyo ATPase Workshop

Hongo Campus, University of Tokyo